A New Paclitaxel Formulation Based on Secretome Isolated from Mesenchymal Stem Cells Shows a Significant Cytotoxic Effect on Osteosarcoma Cell Lines.

Alessia Giovanna Santa Banche NiclotElena MariniIvana FerreroFrancesco BarberoElena RossoIvana Fenoglio Alessandro Barge Augusto Pessina Valentina Cocce Francesca Paino Katia Mareschi Franca Fagioli

Published in: Pharmaceutics (2023)

This proof-of-concept study showed that the conditioned medium isolated from MSCs loaded with PTX had a strong cytotoxic effect on OS cell lines, due to the presence of EV and PTX.

Keyphrases

mesenchymal stem cells
drug delivery
umbilical cord
bone marrow
cell therapy