A New Paclitaxel Formulation Based on Secretome Isolated from Mesenchymal Stem Cells Shows a Significant Cytotoxic Effect on Osteosarcoma Cell Lines.
Alessia Giovanna Santa Banche NiclotElena MariniIvana FerreroFrancesco BarberoElena RossoIvana FenoglioAlessandro BargeAugusto PessinaValentina CocceFrancesca PainoKatia MareschiFranca FagioliPublished in: Pharmaceutics (2023)
This proof-of-concept study showed that the conditioned medium isolated from MSCs loaded with PTX had a strong cytotoxic effect on OS cell lines, due to the presence of EV and PTX.