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A New Paclitaxel Formulation Based on Secretome Isolated from Mesenchymal Stem Cells Shows a Significant Cytotoxic Effect on Osteosarcoma Cell Lines.

Alessia Giovanna Santa Banche NiclotElena MariniIvana FerreroFrancesco BarberoElena RossoIvana FenoglioAlessandro BargeAugusto PessinaValentina CocceFrancesca PainoKatia MareschiFranca Fagioli
Published in: Pharmaceutics (2023)
This proof-of-concept study showed that the conditioned medium isolated from MSCs loaded with PTX had a strong cytotoxic effect on OS cell lines, due to the presence of EV and PTX.
Keyphrases
  • mesenchymal stem cells
  • drug delivery
  • umbilical cord
  • bone marrow
  • cell therapy