Immunophenotypic analysis of lymphocyte subsets in newborns with biotinidase deficiency.

Murat Karaoglan Gulper Nacarkahya Mehmet Keskin Özlem Keskin

Published in: Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology (2020)

This study showed that although there were no differences in the lymphocyte subsets in newborns with BTD, the CD3/CD4 levels were higher in females, and the CD3/CD8 levels were higher in males. In addition, there was a negative correlation between the CD3/CD4 and CD3/CD8 levels in both genders. Although these results indicate sexual dimorphism between CD3/CD4 and CD3/CD8 levels, whether this dissociation is unique to BTD in newborns is not fully clear.

Keyphrases

peripheral blood
pregnant women
low birth weight
gestational age
cord blood
mental health
preterm infants
preterm birth