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New chalcone derivatives as effective against SARS-CoV-2 agent.

Nizami DuranM Fatih PolatDerya Anil AktasM Abdullah AlagozEmrah AyFunda CimenErhan TekBaris AnilSerdar BurmaogluOztekin Algul
Published in: International journal of clinical practice (2021)
Computational analyses identified eight compounds inhibiting each target, with binding affinity scores ranging from -4.370 to -2.748 kcal/mol along with their toxicological, ADME, and drug-like properties.
Keyphrases
  • sars cov
  • molecular docking
  • respiratory syndrome coronavirus
  • signaling pathway
  • dna binding
  • adverse drug
  • drug induced
  • capillary electrophoresis
  • oxide nanoparticles
  • coronavirus disease
  • mass spectrometry