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Headache provocation by nitric oxide in men who have never experienced a headache.

Isa Amalie OlofssonKatrine FalkenbergJes OlesenThomas Folkmann Hansen
Published in: Cephalalgia : an international journal of headache (2021)
We show that men who have never experienced a headache develop a headache when provoked with Isosorbide-5-mononitrate. This indicates that freedom from headache in men is not related to the nitric oxide pathway which is involved in the primary headache disorders.
Keyphrases
  • nitric oxide
  • middle aged
  • hydrogen peroxide
  • nitric oxide synthase