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Allogeneic expanded adipose-derived mesenchymal stem cell therapy for perianal fistulas in Crohn's disease: A case series.

Daniela Cabalzar-WondbergMatthias TurinaLuc BiedermannGerhard RoglerPhilipp Schreiner
Published in: Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland (2021)
This case series demonstrates that the efficacy and safety of darvadstrocel in the ADMIRE trial can be replicated outside a clinical trial. This new modality in the treatment of complex perianal fistulas appears to be a promising therapeutic option for a challenging patient population.
Keyphrases
  • clinical trial
  • bone marrow
  • phase ii
  • mesenchymal stem cells
  • study protocol
  • phase iii
  • stem cell transplantation
  • case report
  • hidradenitis suppurativa
  • open label
  • stem cells
  • low dose
  • high dose
  • hematopoietic stem cell