Prospective randomized comparative study of the effect of pemafibrate add-on or double statin dose on small dense low-density lipoprotein-cholesterol in patients with type 2 diabetes and hypertriglyceridemia on statin therapy.
Tsutomu HiranoToshiyuki HayashiHiroe SugitaAtsuko TamasawaSatoshi GotoMasako TomoyasuTakeshi YamamotoMakoto OharaMichishige TerasakiHideki KushimaYasuki ItoSho-Ichi YamagishiYusaku MoriPublished in: Journal of diabetes investigation (2023)
In patients with type 2 diabetes and hypertriglyceridemia, the addition of pemafibrate to a statin is superior to doubling a statin in reducing sdLDL-C without increasing adverse effects.