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Lack of significant recovery of chloroquine sensitivity in Plasmodium falciparum parasites following discontinuance of chloroquine use in Papua New Guinea.

Makoto SekiharaShin-Ichiro TachibanaMasato YamauchiShoki YatsushiroSteven TiwaraNaoyuki FukudaMie IkedaToshiyuki MoriMakoto HiraiFrancis HombhanjeToshihiro Mita
Published in: Malaria journal (2018)
Eight years of chloroquine withdrawal has not induced a significant recovery of susceptibility in Papua New Guinea. However, an increasing tendency of parasites harbouring chloroquine-susceptible K76 suggests a possibility of resurgence of chloroquine susceptibility in the future.
Keyphrases
  • plasmodium falciparum
  • high glucose
  • oxidative stress
  • trypanosoma cruzi