The antiparasitic drug niclosamide inhibits dengue virus infection by interfering with endosomal acidification independent of mTOR.
Jo-Chi KaoWei-Chun HuangFuTsung-Ting TsaiMin-Ru HoMing-Kai JhanTing-Jing ShenPo-Chun TsengYung-Ting WangChiou-Feng LinPublished in: PLoS neglected tropical diseases (2018)
These results demonstrate that niclosamide diminishes viral infection by hindering endosomal acidification.