Differential expression analysis of clear cell renal cell carcinomas in The Cancer Genome Atlas distinguishes an aggressive subset enriched with chromosomes 7 and 12 gains.
Chin-Chen PanYi-Chen YehYu-Chao WangYen-Hwa ChangPublished in: Histopathology (2020)
Our study demonstrates that genetic data obtained through appropriate molecular methodologies can be a useful adjunct to help predict prognosis. It also provides an example of exploring TCGA to extract meaningful information that can eventually contribute to precision medicine.
Keyphrases
- single cell
- clear cell
- papillary thyroid
- genome wide
- oxidative stress
- big data
- electronic health record
- high grade
- squamous cell carcinoma
- healthcare
- stem cells
- gene expression
- artificial intelligence
- lymph node metastasis
- machine learning
- dna methylation
- mesenchymal stem cells
- young adults
- deep learning
- data analysis