The novel nitric oxide donor PDNO attenuates ovine ischemia-reperfusion induced renal failure.

Kristofer F NilssonJohn SandinLars E GustafssonRobert Frithiof

Published in: Intensive care medicine experimental (2017)

The novel nitric oxide donor PDNO improved renal function after ischemia. PDNO also prevented the persistent reduction in medullary perfusion during reperfusion and improved renal oxygen utilization without severe side effects.

Keyphrases

nitric oxide
nitric oxide synthase
hydrogen peroxide
drug induced
high glucose
acute myocardial infarction
cerebral ischemia
early onset
acute ischemic stroke
heart failure
coronary artery disease
contrast enhanced
magnetic resonance
blood brain barrier
percutaneous coronary intervention