The effect of Cyclophilin D depletion on liver regeneration following associating liver partition and portal vein ligation for staged hepatectomy.

Noemi DaradicsGergo HorvathLaszlo TretterAgnes PaalAndras FulopAndras BudaiAttila Szijarto

Published in: PloS one (2022)

Our study demonstrates the beneficial effect of CypD depletion on the mitochondrial vulnerability following ALPPS. Based on our results we propose that CypD inhibition should be further investigated as a possible mitochondrial therapy following ALPPS.

Keyphrases

oxidative stress
stem cells
climate change
atomic force microscopy
high resolution