Crucial role of oxidative stress in bactericidal effect of parthenolide against Xanthomonas oryzae pv. oryzae.

Shu XuXingzeng ZhaoFei LiuYan CaoBi WangXiangyun WangMin YinQizhi WangXu Feng

Published in: Pest management science (2018)

PTL is a promising lead compound for developing bactericide against Xoo. PTL rapidly reacts with GSH, resulting in disturbed GSH/GSSG balance in Xoo, which causes ROS accumulation, leading to cell death. Oxidative stress plays a critical role in the bactericidal effect of PTL against Xoo. © 2018 Society of Chemical Industry.

Keyphrases

oxidative stress
cell death
dna damage
fluorescent probe
diabetic rats
ischemia reperfusion injury
induced apoptosis
cell cycle arrest
reactive oxygen species
signaling pathway
heat shock protein