The N6 -methyladenosine (m6 A) erasers alkylation repair homologue 5 (ALKBH5) and fat mass and obesity-associated protein (FTO) are prognostic biomarkers in patients with clear cell renal carcinoma.

Alexander StrickFelix von HagenLarissa GundertNiklas KlümperYuri TolkachDoris SchmidtGlen KristiansenMarieta TomaManuel RitterJoerg Ellinger

Published in: BJU international (2020)

Taken together, our present data indicate that the m6 A-demethylases ALKBH5 and FTO are dysregulated in ccRCC and could be used as prognostic biomarkers.

Keyphrases

clear cell
metabolic syndrome
insulin resistance
adipose tissue
weight loss
type diabetes
electronic health record
high fat diet induced
artificial intelligence