Telomerase Activation and ATRX Mutations Are Independent Risk Factors for Metastatic Pheochromocytoma and Paraganglioma.
Sylvie JobIrena DraskovicNelly BurnichonAlexandre BuffetJérôme CrosCharles LépineAnnabelle VenisseEstelle RobidelVirginie VerkarreTchao MeatchiMathilde SibonyLaurence AmarJérôme BertheratAurélien de ReynièsJosé-Arturo Londono-VallejoJudith FavierLuis Jaime Castro-VegaAnne-Paule Gimenez-RoqueploPublished in: Clinical cancer research : an official journal of the American Association for Cancer Research (2018)
Assessment of telomerase activation and ATRX mutations could be used to identify metastatic PPGLs, particularly in tumors at high risk of progression.