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Incidence, clinicopathological features and fusion transcript landscape of translocation renal cell carcinomas.

Marion ClasseGabriel G MaloufXiaoping SuHui YaoErika J ThompsonDenaha J DossValérie GrégoireJulien LenobinJean-Christophe FantoniHelene Sudour-BonnangeDavid KhayatSébastien AubertNizar M TannirXavier Leroy
Published in: Histopathology (2017)
We identified a new fusion partner, GRIPAP1. The prognostic role of transcript type could not be determined because our number of cases was too small. Four patients (19%) died of the disease, all of which presented with a lymph node involvement at diagnosis. We confirm that tRCC can be an aggressive tumour, especially those of advanced clinical stage.
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