SMIFH2 inhibition of platelets demonstrates a critical role for formin proteins in platelet cytoskeletal dynamics.
Hannah L H GreenMalou ZuidscherwoudeFawaz AlenazyChristopher W SmithMarkus BenderSteven G ThomasPublished in: Journal of thrombosis and haemostasis : JTH (2020)
These data therefore demonstrated an important role for formin-mediated actin polymerization in platelet spreading and highlighted the importance of formins in cross-talk between the actin and tubulin cytoskeletons.