Comparison of ischemic preconditioning and BotulinumA Toxin injection for the prevention of ischemia-reperfusion injury in musculocutaneous flaps

Handan Derebaşınlıoğlu Anil Demİröz Yağmur Aydin Hakan Ekmekçi Özlem Balcı Ekmekçi Övgü Aydın Levent Cankorkmaz

Published in: Turkish journal of medical sciences (2020)

Findings show that botulinum has a protective effect against the ischemia-reperfusion injury via increased NO and decreased MPO levels in tissue. Based on tissue NO levels, ischemic preconditioning was significantly higher than botulinum.

Keyphrases

ischemia reperfusion injury
oxidative stress
cerebral ischemia
escherichia coli
ultrasound guided
soft tissue
subarachnoid hemorrhage
brain injury
blood brain barrier
breast reconstruction
clinical evaluation