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Clinical features, treatment outcomes and mortality risk of tuberculosis sepsis in HIV-negative patients: a systematic review and meta-analysis of case reports.

Roméo Bayodé AdegbiteNadege O M Elegbede-AdegbiteJean R EdoaYabo J HonkpehedjiJeannot F ZinsouJean Claude Dejon-AgobéAyola A AdegnikaMartin P Grobusch
Published in: Infection (2022)
Our review showed TBS occurred in HIV-negative patients and some of them have no known immunocompromised underlying co-morbidity. TBS might not be rare as clinicians thought but might be prone to be missed. In endemic settings, M. tuberculosis etiology of sepsis should be accounted for early, irrespective of HIV infection status.
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