Bowel damage and disability in Crohn's disease: a prospective study in a tertiary referral centre of the Lémann Index and Inflammatory Bowel Disease Disability Index.
Clémentine Lauriot Dit PrevostMustapha AzahafMaria NachuryJulien BrancheRomain GerardPauline WilsThomas LambinPierre DesreumauxOlivier ErnstBenjamin ParientePublished in: Alimentary pharmacology & therapeutics (2020)
This is the first study to prospectively evaluate the Lémann Index and the IBD Disability Index in a large cohort of CD patients in a tertiary centre. Early introduction of anti-TNF treatment was associated with lower bowel damage scores, and no correlation was observed between the Lémann Index and the IBD Disability Index. Further dedicated prospective studies are necessary to confirm these results.