Anti-inflammatory effects of Morus alba Linne bark on the activation of toll-like receptors and imiquimod-induced ear edema in mice.
Lin UmeyamaBesse HardiantiShiori KasaharaDya Fita DibweSuresh AwaleSatoru YokoyamaYoshihiro HayakawaPublished in: BMC complementary medicine and therapies (2021)
Our study suggests that the anti-inflammatory effects of MabE on the activation of the macrophage cell line RAW246.7 by TLRs and IMQ-induced ear edema are through the inhibition of NF-κB activation and IL-17A-producing γδT cells, respectively.