Exploring C-peptide loss in type 1 diabetes using growth curve analysis.
Rachel Elizabeth Jane BesserJohnny LudvigssonPeter C HindmarshTim J ColePublished in: PloS one (2018)
SITAR growth curve analysis is a useful tool to assess CP loss in type 1 diabetes, explaining patient differences in terms of their mean level and rate of fall. A definition of rapid CP loss could be based on a quantile of the rate of fall distribution, allowing better understanding of factors determining CP loss and stratification of patients into targeted therapies.