Atypical Neurofibromas reveal distinct epigenetic features with proximity to benign peripheral nerve sheath tumor entities.
Catena KresbachMatthias DottermuschAlicia EckhardtInka RistowPetros PaplomatasLea AltendorfAnnika K WefersMichael BockmayrSarra BelakhouaIvy TranLara PohlSina NeyaziHelena BodeSaid C FarschtschiLennart WellReinhard E FriedrichDavid ReussMatija SnuderlChristian HagelVictor-Felix MautnerUlrich SchüllerPublished in: Neuro-oncology (2023)
Our data suggest that ANF with varying histological morphology show distinct epigenetic similarities and cluster in proximity to benign peripheral nerve sheath tumor entities. Future investigations should pay special respect to correlating this methylation pattern to clinical outcome.