Clinical and patient reported trajectories at end-of-life in older patients with advanced CKD.
Nicholas C ChesnayeFergus J CaskeyFriedo W DekkerEsther N M de RooijMarie EvansOlof HeimburgerMaria PippiasClaudia TorinoGaetana PortoMaciej SzymczakChristiane DrechslerChristoph WannerKitty J Jagernull nullPublished in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association (2023)
We identified clinically relevant physiological accelerations in patient trajectories that began approximately 6 to 12 months prior to death, which are likely multifactorial in nature, but correlate with a surge in hospitalizations. Further research should focus on how to effectively use this knowledge to inform patient and family expectations, to benefit the planning of (end-of-life) care, and to establish clinical alert systems.