[Adjuvant effect of dispersed fullerene C60 on the immune response to constructs harboring amino acid and nucleotide sequences of hepatitis C virus nonstructural NS5B protein].
Olga V MasalovaEkaterina I LesnovaSergey M AndreevNadezhda ShershakovaVyacheslav V KozlovK Y PermyakovaNatalya A DemidovaVladimir T Valuev-EllistonE A TuretskiyAlexander V IvanovT N NikolaevaM R KhaitovAlexander V ProninVladimir T Valuev-EllistonPublished in: Voprosy virusologii (2023)
Dispersed fullerene dnC60 is a promising adjuvant for increasing the immunostimulating activity of weakly immunogenic proteins including surface and other HCV proteins, important for a protective response. Further research is needed to enhance the ability of dnC60 to boost the cellular immune response to the components of the candidate vaccine.