Pharmacodynamic Drug-Drug Interactions and Bleeding Outcomes in Patients with Atrial Fibrillation Using Non-Vitamin K Antagonist Oral Anticoagulants: a Nationwide Cohort Study.

Maxim GrymonprezAndreas CapiauStephane SteurbautKoen BousseryEls MehuysAnnemie SomersMirko PetrovicTine L De BackerLies Lahousse

Published in: Cardiovascular drugs and therapy (2023)

inhibitors and corticosteroids, was associated with higher major, gastrointestinal, urogenital, and other bleeding risks in NOAC-treated AF patients. Remarkably, higher intracranial bleeding risks were observed with SSRI/SNRIs and corticosteroids.

Keyphrases

atrial fibrillation
oral anticoagulants
end stage renal disease
newly diagnosed
ejection fraction
chronic kidney disease
human health
prognostic factors
patient reported outcomes
adipose tissue
risk assessment
patient reported
insulin resistance