The impact of genetic risk on the prevalence of advanced fibrosis and cirrhosis in prospectively assessed patients with type 2 diabetes.

Lana BridiSaaket AgrawalKaleb TesfaiEgbert MadambaRicki BettencourtLisa M RichardsAmit V KheraStephen Caldwell Veeral H Ajmera

Published in: Alimentary pharmacology & therapeutics (2024)

Utilising a well-phenotyped, prospective cohort of adults with T2DM, we found that adding an assessment of genetic risk to recommendations to screen at-risk populations may improve risk prediction.

Keyphrases

genome wide
risk factors
copy number
high throughput
type diabetes
clinical practice
gene expression
skeletal muscle
insulin resistance
weight loss
genetic diversity