Impact of linkage disequilibrium heterogeneity along the genome on genomic prediction and heritability estimation.

Duanyang RenXiaodian CaiQing LinHaoqiang YeJinyan TengJiaqi LiXiangdong DingZhe Zhang

Published in: Genetics, selection, evolution : GSE (2022)

Grouping SNPs based on regional LD to construct the LD-stratified multicomponent model can effectively eliminate the adverse effects of LD heterogeneity among regions, and greatly improve the efficiency of high-density SNP data for genomic prediction and heritability estimation.

Keyphrases

high density
genome wide
copy number
single cell
dna methylation
electronic health record
big data
genome wide association
emergency department
artificial intelligence
hepatitis c virus