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Inhibition of METTL4: Targeting a Methyltransferase that Alleviates Heart Failure by Modulating Excess N6-Methyladenine in Mitochondrial DNA.
Jiaqi Wang
Michail Spanos
Yihua Bei
Published in:
Journal of cardiovascular translational research (2024)
Keyphrases
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mitochondrial dna
heart failure
copy number
cancer therapy
signaling pathway
left ventricular
cardiac resynchronization therapy
mouse model
acute heart failure
atrial fibrillation
genome wide
gene expression
dna methylation