Intravenous Anesthetic Protects Hepatocyte from Reactive Oxygen Species-Induced Cellular Apoptosis during Liver Transplantation In Vivo.
Weifeng YaoXue HanYihan ZhangJianqiang GuanMian GeChaojin ChenShan WuJiaxin ChenGangjian LuoPin-Jie HuangZiqing HeiPublished in: Oxidative medicine and cellular longevity (2018)
Liver transplantation leads to severe inflammation and oxidative stress with NADPH oxidase activation. Propofol postconditioning reduces liver I/R injury after liver transplantation partly via inhibiting NADPH oxidase Nox2 and the subsequent inflammation and oxidative stress.