A robust carbon dot-based antibacterial CDs-PVA film as a wound dressing for antibiosis and wound healing.

Developing highly effective antibacterial films to promote wound healing remains a huge challenge. Herein, homogeneous and self-standing CDs-PVA composite films (PVA 3 , PVA 5 and PVA 8 ) were constructed by doping various mass ratios (3, 5 and 8 wt%) of carbon dots (CDs) into polyvinyl alcohol (PVA), which had no cracks or macroscopic defects. Moreover, the robust mechanical strength and flexibility enabled them to be cut into diverse patterns as required, which provided unique advantages for being employed as a wound dressing. PVA 5 and PVA 8 were powerful broad-spectrum bactericides and they could kill both Gram-negative bacteria and Gram-positive bacteria like Escherichia coli ( E. coli ) and Staphylococcus aureus ( S. aureus ) with the antibacterial efficacy over 90.0%. More significantly, the biocompatible films could be readily processed into a "band-aid" type dressing for wound healing. The PVA 5 band-aids were just pasted on the wounds for two days and then removed, and the wounds were completely closed after fourteen days. Neither introducing any metals or antibiotics, nor with the help of any external activation, these kinds of CD-based films have the strengths of low cost, being easy to use, excellent biocompatibility and outstanding antibacterial performance, and are desirable wound dressings for various skin injuries.