Investigating the role of expectancy in caffeine withdrawal using the balanced placebo design.

Laura M JulianoPeter G KardelPaul T HarrellChristine MuenchKathryn C Edwards

Published in: Human psychopharmacology (2019)

These findings confirm a strong pharmacological basis for caffeine withdrawal and an important role of cognition in drug craving. Future research should investigate the role of expectancy in drug withdrawal and craving and the potential use of expectancy manipulations in symptom prevention and management.

Keyphrases

adverse drug
mild cognitive impairment
drug induced
double blind
climate change
human health
patient reported
phase iii
open label