Obesity, hyperfiltration and early kidney damage: a new formula for the estimation of creatinine clearance.

Alessio BasoloGuido SalvettiDomenico GianneseSusanna Bechi GenzanoGiovanni CeccariniRiccardo GianniniGianluca SotgiaPaola FierabracciPaolo PiaggiFerruccio Santini

Published in: The Journal of clinical endocrinology and metabolism (2023)

In patients with obesity the glomerular filtration rate increases with body weight, and it is associated with the presence of albuminuria, suggesting an early kidney injury. We propose a novel formula that improves the accuracy of eCrCl to avoid missed diagnoses of hyperfiltration in patients with obesity.

Keyphrases

insulin resistance
body weight
metabolic syndrome
weight loss
high fat diet induced
type diabetes
weight gain
uric acid
human milk
adipose tissue
preterm infants