Peripheral blood mononuclear cells-expressed miRNA profiles derived from children with metabolic-associated fatty liver disease and insulin resistance.

Maddi Osés-Recalde María MedranoJavier Margareto SanchezMaria P PortilloConcepcion Maria Aguilera Signe Altmäe Idoia Labayen Goñi

Published in: Pediatric obesity (2022)

Our study results suggest circulating miR-660-5p as a potential biomarker of the presence of MAFLD in preadolescent children while circulating miR-320a, miR-142-3p, miR-190a-5p, miR-374a-5p and let-7 family miRNAs could serve as potential biomarkers of IR in children.

Keyphrases

young adults
insulin resistance
cell proliferation
long non coding rna
type diabetes
adipose tissue
metabolic syndrome
high fat diet
long noncoding rna
weight loss