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UDP-glucuronosyltransferase genetic variation in North African populations: a comparison with African and European data.

Apolonia NovilloMaría GaibarAlicia Romero-LorcaHassen ChaabaniNadir AmirPedro MoralMaría Esther Esteban TornéAna Fernández-Santander
Published in: Annals of human biology (2019)
North African populations show a high frequency of carriers of UGT2B15523Thr, a variant linked to an increased risk of prostate cancer. High Atlas Moroccans and Algerians show low frequency of UGT2B17del, a variant associated with high concentrations of testosterone and oestradiol.
Keyphrases
  • high frequency
  • prostate cancer
  • transcranial magnetic stimulation
  • tertiary care
  • radical prostatectomy
  • genetic diversity
  • big data
  • machine learning
  • replacement therapy
  • deep learning
  • smoking cessation