Mettl3 promotes oxLDL-mediated inflammation through activating STAT1 signaling.

Zhenwei LiQingqing XuNing HuangfuXiaomin ChenJianhua Zhu

Published in: Journal of clinical laboratory analysis (2021)

These results indicate that Mettl3 promotes oxLDL-triggered inflammation through interacting with STAT1 protein and mRNA in RAW264.7 macrophages, suggesting that Mettl3 may be as a potential target for the clinical treatment of AS.

Keyphrases

oxidative stress
cell proliferation
signaling pathway
binding protein
protein protein
human health
small molecule