Association between urinary biomarkers MMP-7/TIMP-2 and reduced renal function in children with ureteropelvic junction obstruction.

Hsin-Hsiao S WangPatricia S ChoHui ZhiStephen A KostelShannon DiMartinoAdelle M DagherKylie H DavisLily D CabourAshley ShimmelJames LeeJohn W FroehlichDavid ZurakowskiMarsha A MosesRichard S Lee

Published in: PloS one (2022)

Combination of urinary MMP-7 and TIMP-2 can identify reduced renal function in UPJO patients. With the high sensitivity cutoffs, patients can be categorized into high risk (aggressive management) versus lower risk (observation).

Keyphrases

end stage renal disease
ejection fraction
newly diagnosed
chronic kidney disease
young adults
prognostic factors
cell migration
patient reported outcomes