Similar genomic proportions of copy number variation within gray wolves and modern dog breeds inferred from whole genome sequencing.

Aitor Serres-ArmeroInna S PovolotskayaJavier QuilezOscar RamirezGabriel SantpereLukas F K KudernaJessica Hernandez-RodriguezMarcos Fernandez-CallejoDaniel Gomez-SanchezAdam H FreedmanZhenxin FanJohn NovembreArcadi NavarroAdam BoykoRobert WayneCarles VilàBelen Lorente-GaldosTomas Marques-Bonet

Published in: BMC genomics (2017)

This work is the first comparison of genome wide CNV patterns in domestic and wild canids using whole-genome sequencing data and our findings contribute to study the impact of novel kinds of genetic changes on the evolution of the domestic dog.

Keyphrases

copy number
genome wide
mitochondrial dna
dna methylation
electronic health record
genetic diversity
big data
gene expression
machine learning
deep learning
data analysis