Investigating the causal relationship between allergic disease and mental health.
Ashley Budu-AggreySally JoyceNeil Martin DaviesLavinia PaternosterMarcus R MunafoSara J BrownJonathan EvansHannah M SallisPublished in: Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology (2021)
Using MR, we were unable to replicate most of the phenotypic associations between allergic disease and mental health. Any causal effects we detected were considerably attenuated compared with the phenotypic association. This suggests that most comorbidity observed clinically is unlikely to be causal.