Genetic polymorphisms in the Interleukins IL1B, IL4, and IL6 are associated with concomitant periodontitis and type 2 diabetes mellitus in Brazilian patients.
Thamiris CirelliRafael NepomucenoAna Cláudia S RiosSilvana R P OrricoJoni Augusto CirelliLeticia Helena TheodoroSilvana P BarrosRaquel Mantuaneli Scarel CaminagaPublished in: Journal of periodontal research (2020)
Some SNPs in the IL1B, IL4, and IL6 genes demonstrated sex-influenced association with concomitant periodontitis and T2DM, increasing the evidence of a common genetic component between these diseases and contributing with the understanding of their common pathogenic mechanisms.