Identification of Specific Cervical Cancer Subtypes and Prognostic Gene Sets in Tumor and Nontumor Tissues Based on GSVA Analysis.

Zihang ZhongYuanyuan WangJian YinSenmiao NiWen LiuRui Geng JinHui Liu Jianling Bai Hao Yu

Published in: Journal of oncology (2022)

Three novel subtypes and two prognostic gene sets were identified. 15 hub genes for T gene set and 5 hub genes for N gene set were discovered. Based on these findings, we can develop more and more effective treatments for cervical cancer patients. Based on the gene enriched pathways, we can development specific drugs targeting the pathways.

Keyphrases

genome wide
genome wide identification
copy number
bioinformatics analysis
genome wide analysis
dna methylation
gene expression
transcription factor