pH-responsive theranostic nanocomposites as synergistically enhancing positive and negative magnetic resonance imaging contrast agents.
Xi HuangYaping YuanWeiwei RuanLianhua LiuMaili LiuShizhen ChenXin ZhouPublished in: Journal of nanobiotechnology (2018)
The synthesized nanocomposites exhibited highly sensitive MRI contrast function no matter in solution, cells or in vivo by synergistically enhancing positive and negative magnetic resonance imaging signals. The nanocomposites showed great potential for integrating imaging diagnosis and drug controlled release into one composition and providing real-time imaging with greatly enhanced diagnostic accuracy during targeted therapy.
Keyphrases
- magnetic resonance imaging
- contrast enhanced
- high resolution
- magnetic resonance
- reduced graphene oxide
- computed tomography
- induced apoptosis
- carbon nanotubes
- diffusion weighted imaging
- fluorescence imaging
- photodynamic therapy
- visible light
- emergency department
- oxidative stress
- cell proliferation
- simultaneous determination
- adverse drug
- electronic health record
- tandem mass spectrometry