Long-term cognitive function changes with non-vitamin K oral anticoagulants in older patients with atrial fibrillation. A multicenter cohort study.
Giuseppe ArmentaroGraziella D'ArrigoDaniele PastoriGiulia CrudoMario DaidoneLuca SoraciCarlo Alberto PasturaMarcello DivinoAnnalisa PitinoMercedes GoriGiovanni TripepiEgidio ImbalzanoAndrea CorsonelloPasquale PignatelliFrancesco AndreozziAntonino TuttolomondoAngela SciacquaPublished in: European journal of clinical investigation (2024)
In older patients with atrial fibrillation, the use of NOACs was associated with a smaller decline of cognitive function over time compared to the VKAs, regardless that patients in the NOACs group were older and with a higher burden of comorbidities.