Our study is the largest series today describing the association between HLA sensitization and ECMO therapy. We suggest that interaction between the immune system and ECMO circuit contributes to allosensitization pretransplant, similar to that occurring with ventricular assist device. Further work is needed to better characterize the incidence of HLA sensitization in a multicenter cohort and to identify potentially modifiable factors associated with HLA sensitization.
Keyphrases
- extracorporeal membrane oxygenation
- acute respiratory distress syndrome
- respiratory failure
- end stage renal disease
- chronic kidney disease
- ejection fraction
- heart failure
- newly diagnosed
- peritoneal dialysis
- mechanical ventilation
- stem cells
- patient reported outcomes
- mesenchymal stem cells
- catheter ablation
- double blind