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Establishing electroporation thresholds for targeted cell specific cardiac ablation in a 2D culture model.

Sahar AvazzadehMahshid H DehkordiPeter OwensAmirhossein JalaliBarry O'BrienKen CoffeyMartin O'HalloranHoward O FernheadDavid KeaneLeo R Quinlan
Published in: Journal of cardiovascular electrophysiology (2022)
This study presents important findings on the differences in the susceptibility of neurons and cardiomyocytes to irreversible electroporation. Cell type alone yielded selective and different dynamics in terms of the evolution and signaling mechanism of cell death in response to electroporation.
Keyphrases
  • cell death
  • single cell
  • cell therapy
  • spinal cord
  • left ventricular
  • stem cells
  • heart failure
  • atrial fibrillation
  • mesenchymal stem cells
  • radiofrequency ablation
  • bone marrow
  • catheter ablation