Diabetic Encephalopathy Affecting Mitochondria and Axonal Transport Proteins.
Maryam Eslami GharaatiArezo NahavandiTorandokht Baluchnejad MojaradMehrdad RoghaniPublished in: Basic and clinical neuroscience (2020)
KIF5b mRNA up-regulation in hippocampal neurons of STZ-diabetic rats is a factor that can be involved in abnormal axonal transport and decreased MMP, leading to impairment of mitochondrial function. These manifestations showed mitochondrial dysfunction in diabetes and resulted in abnormal behavioral tests and diabetic encephalopathy.