Loss of VOPP1 Contributes to BET Inhibitor Acquired Resistance in Non-Small Cell Lung Cancer Cells.
Lin SunQian WuXia-Juan HuanChang-Qing TianYing-Qing WangZe-Hong MiaoPublished in: Molecular cancer research : MCR (2022)
Based on these results, for the first time, we establish a causal link from VOPP1 loss to BCL-2 gain and then to BETi resistance, which provides new insights into BETi resistance and paves the way for further testing to circumvent BETi resistance.
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