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m 6 A RNA methylation controls salivary gland epithelial cell function and has a protective role in Sjögren's disease.

Frederic TruffinetAlejandro Arco-HiervesHosnia ShalabiJuliette PascaudPaul MazetElodie RivièreSacha E Silva-SaffarLucilla FabbriSophie LeboucherLaetitia BesseCedric MessaoudiAurore AttinaAlexandre DavidStéphan VagnerGaetane NocturneXavier MarietteRami Bechara
Published in: Annals of the rheumatic diseases (2024)
A modifications in SGEC in response to inflammatory triggers favour the formation of dsRNA, potentially amplifying the interferon loop and contributing to SjD pathogenesis.
Keyphrases
  • dendritic cells
  • oxidative stress
  • genome wide
  • dna methylation
  • transcription factor
  • immune response
  • rheumatoid arthritis