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Patient-Derived Triple-Negative Breast Cancer Organoids Provide Robust Model Systems That Recapitulate Tumor Intrinsic Characteristics.

Sonam BhatiaMelissa KramerSuzanne RussoPayal NaikGayatri ArunKyle BrophyPeter AndrewsCheng FanCharles M PerouJonathan PreallTaehoon HaDennis PlenkerDavid A TuvesonArvind RishiJohn E WilkinsonW Richard McCombieKaren KostroffDavid L Spector
Published in: Cancer research (2022)
A comprehensive analysis of patient-derived organoids of TNBC provides insights into cellular heterogeneity and mechanisms of tumorigenesis at the single-cell level.
Keyphrases
  • single cell
  • rna seq
  • high throughput
  • induced pluripotent stem cells