Differential SLC6A4 methylation: a predictive epigenetic marker of adiposity from birth to adulthood.

Karen A LillycropEmma S GarrattPhilip TitcombePhillip E MeltonRobert J S MurraySheila J BartonRebecca Clarke-HarrisPaula M CostelloJoanna D HolbrookJames C HopkinsCaroline E ChildsCarolina Paras-ChavezPhilip C CalderTrevor A MoriLawrie BeilinGraham C BurdgePeter D GluckmanHazel M InskipNicholas C HarveyMark A HansonRae-Chi HuangCyrus Coopernull nullKeith M Godfrey

Published in: International journal of obesity (2005) (2019)

These data suggest that altered methylation of CpG loci within SLC6A4 may provide a robust marker of adiposity across the life course.

Keyphrases

dna methylation
genome wide
insulin resistance
gene expression
weight gain
electronic health record
depressive symptoms
big data
gestational age
type diabetes
adipose tissue
metabolic syndrome
machine learning
body mass index
pregnancy outcomes