Lenticular changes in eyes with advanced intraocular retinoblastoma: A histopathological study of 48 enucleated eyes.

Eyes with advanced RB can harbor cataract in 58% cases, though most of these are subclinical. Clinically significant cataract may be evident in only 18% cases. Increased tumor necrosis is associated with the development of cataractous changes in RB cases.